Basic Information
VIS ID
TVIS10014629
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1598
Orient
+
Integrated sequence
ATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCT| |GCACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTG
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
62325166/62291262 (Hg38)
End
62325166/62291262 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/4518910; hsa-mir-11401/Downstream/4911059;
Nearest TSS
ENST00000527434/Upstream/254227; ENST00000415422/Downstream/305110;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/254532, chr16-CpG: 19/Downstream/2659516
Upstream sequence
ggtgtagaatcactgtagatcccagtcagaattaaaaaaaaaatcacaaggcatatcatagtaaaactacaagatatcagagataaggggaatatatatc
Downstream sequence
ctttctttctggttgcttttaagattacctgagaaaaatgttcaacaattataaataacagttgtcttctcaataaagaaacataacagactgttacttt
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate