Basic Information
VIS ID
TVIS10014631
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1824
Orient
-
Integrated sequence
AAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAA
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
80892946/80427261 (Hg38)
End
80892946/80427261 (Hg38)
Orient
+
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/3367059; hsa-mir-11399/Downstream/4706533;
Nearest TSS
ENST00000473358/Upstream/52640; ENST00000418041/Downstream/108494;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/96060, chr1-CpG: 281/Downstream/1373052
Upstream sequence
CCAGTAGTCAATCAATGTATAAATAGAACAGTAACTATCAAGTATGCAAAATTTCAAACGCTAACTCTGTTCCCATGATCATTAACATGTGAGCTCTTTC
Downstream sequence
AGTATTTCAGATTGCAATAATTTGAAGGGTAGAGAAACTATACATGTAGCCTCAATTTAGGACAAAAAAACAAAAAGAAAGAAAAAATATATAGAGAGAA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate