Basic Information
VIS ID
TVIS10014634
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
418
Orient
+
Integrated sequence
CCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGCTATCGCTGGATGTGTCTGCGGCGTTTTATCATATTCCTCTTCATCCTGCTG| |CTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCA
Host Sequence
Chromosome
chr5
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
16264250/16264141 (Hg38)
End
16264250/16264141 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10397/Upstream/328881; hsa-mir-103a-1/Downstream/891789;
Nearest TSS
ENST00000502646/Upstream/83379; ENST00000513041/Downstream/164395;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/83830, chr5-CpG: 105/Downstream/200988
Upstream sequence
GCCACGTGGGAAGCGCGGTCCTGGGCGTCTGTGCCCGCGAATCCACTGGGAGCCCGGCCTGGCCCCGACAGCGCAGCTGCTCCGGGCGGACCCGGGGGTC
Downstream sequence
cctcctgttcttatctacttatttgtgtggaaaactttctcagacaacatttttaaaaatttttttcaacttttattttaagtctgggggtacgtgtaca
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate