Basic Information
VIS ID
TVIS10014635
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1182
Orient
+
Integrated sequence
GCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTGCACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTG| |TTTGCTGACGCAACCCCCACTGGATGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCC
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
36749272/36749170 (Hg38)
End
36749272/36749170 (Hg38)
Orient
-
Fragile sites / regions
FRA5A
Nearest miRNA
hsa-mir-10397/Upstream/601182; hsa-mir-103a-1/Downstream/1808332;
Nearest TSS
ENST00000502646/Upstream/23975; ENST00000505998/Downstream/113047;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/3690, chr5-CpG: 144/Downstream/126655
Upstream sequence
GTGGGAAGCGCGGTCCTGGGCGTCTGTGCCCGCGAATCCACTGGGAGCCCGGCCTGGCCCCGACAGCGCAGCTGCTCCGGGCGGACCCGGGGGTCTGGGC
Downstream sequence
aggacttttcccattgcaatggatttagcaattaggaccccaaactaaggatgttaagcacccgacatactaaagacagctgaatacaactagaggcaag
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate