Basic Information
VIS ID
TVIS10014636
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1134
Orient
+
Integrated sequence
ATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATAT| |CTGCACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACTGGATGGGGCTTGGCCATAGGCCATCGGCGCA
Host Sequence
Chromosome
chr5
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
62473247/63177420 (Hg38)
End
62473247/63177420 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10397/Upstream/3473717; hsa-mir-103a-1/Downstream/8992047;
Nearest TSS
ENST00000502646/Upstream/576191; ENST00000504296/Downstream/784713;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/764191, chr5-CpG: 32/Downstream/781797
Upstream sequence
CTGTTTTCAGAGTTGTGTACTCCCTACAGTTACTAATGTGGCTCCTCATGCACCTGCAGAATCTGTAGCCACTGGATTTGAATTACATTACTTTCAGTTT
Downstream sequence
accatattccctttccagagttcgaaagtttgataaagtgtgaattttgaaacccatttgtccccaaggattGTAGACTGTAGTTGATTATTTCTGTGTT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
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