Basic Information
VIS ID
TVIS10014639
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
140
Orient
-
Integrated sequence
AGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGG| |ACCCTGCACAGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACC
Host Sequence
Chromosome
chr4
Cytoband
p15.31
Reference genome
GRCh37/hg19
Start
19502309/19500686 (Hg38)
End
19502309/19500686 (Hg38)
Orient
+
Fragile sites / regions
FRA4D
Nearest miRNA
hsa-mir-12113/Upstream/5872729; hsa-mir-12115/Downstream/1027589;
Nearest TSS
ENST00000502981/Upstream/43692; ENST00000508824/Downstream/253905;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1478036, chr4-CpG: 284/Downstream/750967
Upstream sequence
aactccaccaaaaaactaatagaattgataaatttggtaaagttgcaggatacaaaagcaacatacaaaaattagtagcaattttatatgtcagcagtga
Downstream sequence
TGATTCCTATTTTTTTCTGTGTCTTTCCCACATCCTTTGTCCTTTAACAGCAAGATGATCCAATAGTGTTTATCAAAAAATAAGTGTTTTTGTAAATCAG
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate