Basic Information
VIS ID
TVIS10014640
Fusion event
HBV-GRXCR1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1793
Orient
+
Integrated sequence
CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT
Host Sequence
Chromosome
chr4
Cytoband
p13
Reference genome
GRCh37/hg19
Start
42950229/42948212 (Hg38)
End
42950229/42948212 (Hg38)
Orient
-
Location type
Intronic
Target gene
GRXCR1
Nearest miRNA
hsa-mir-12113/Upstream/2446093; hsa-mir-1243/Downstream/4704457;
Nearest TSS
ENST00000502981/Upstream/54945; ENST00000505575/Downstream/185655;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/290679, chr4-CpG: 174/Downstream/1499157
Upstream sequence
TGTAATAAGTGAGAGGACAAAGGAAGAAAGTGTTATTGATATAGAGTACCATTAACCAACTTTGTGTGTATATGTGTACCTCTAGAATAGATTTATTTTG
Downstream sequence
TTTTCACAGCAATTTCTAGGGCTTTTTTTTTTTTTTAATACCTGAAAGGAAAGCATATTGCAAGATAAGAGATAGAAACCAGTAGAAAAGATAGATAAAG
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate