VISDB Viral Integration Site DataBase

VIS ID

TVIS10014641

Fusion event

HBV-ZNF318 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1375

Orient

-

Integrated sequence

GAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCAAAACTTATCGGGACTGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTCCCAT| |GGCTGCTCGGGTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTT

Chromosome

chr6

Cytoband

p21.1

Reference genome

Start

End

43307979/43340241 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-744-5p ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-197-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-410-3p ; hsa-mir-5683 ; hsa-mir-382-5p ; hsa-mir-495-5p ; hsa-mir-2681-5p

Nearest miRNA

hsa-mir-10398/Upstream/1606631; hsa-mir-10524/Downstream/94301;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/31320, chr6-CpG: 148/Downstream/28501

Upstream sequence

tgagaaacagaagctgccaggggcaaccttacagggtgggcaccggacaaagaagtagccggacctcactcttctctgccgccgaccttctgctgctgct

Downstream sequence

GTTCCTTTTATTTTCAGCTTTTTCAGGGGAGTTCCTACCCTCAGAGAGTTGGTCTTCTAATTTCTCAGAGACCTTGTCATCCTCCTTTACTTCTTTCACA