VISDB Viral Integration Site DataBase

VIS ID

TVIS10014643

Fusion event

HBV-chr17 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2413

Orient

-

Integrated sequence

TATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCG| |CGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATCCCTTGGACTCATAAGGTGGGAAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTC

Chromosome

chr17

Cytoband

q12

Reference genome

Start

End

37006422/38850169 (Hg38)

Orient

-

Location type

Intronic

Target gene

C17orf98 ; RPL23

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-615-3p ; hsa-mir-503-5p ; hsa-mir-183-5p ; hsa-mir-3200-3p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6872-3p ; hsa-mir-3934-5p ; hsa-mir-6504-3p ; hsa-mir-552-3p ; hsa-mir-1228-3p ; hsa-mir-1285-3p ; hsa-mir-25-3p ; hsa-mir-3187-5p ; hsa-mir-32-5p ; hsa-mir-335-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4325 ; hsa-mir-508-5p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6849-3p ; hsa-mir-6860 ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-1180/Upstream/24277; hsa-mir-10226/Downstream/64810;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/8761, chr17-CpG: 46/Downstream/3049

Nearest cancer related gene

RPL23(OG, No orient, 0)

Upstream sequence

CAAACAAATACTTTTTAATGGGTTTAGTTTTTTTTTTTATTTTTTACAAATATACTGGAGAATCATGCAATGCTGCCAGCATTGGATGCAATCCGGGGCC

Downstream sequence

ACAAGTCTGCACACTCCTTTGCTACTGGTCCTGTAATGGCAGAACCTGCATTAAAaaaataaaataaaataaaataaaaACATGTGGGGGACAGATTAAG