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VISDB
Viral Integration Site DataBase
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TVIS10014649
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014649
Fusion event
HBV-TERT integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
19
Orient
-
Integrated sequence
CTCCACAACATTCCACCAA| |GCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGT
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1295221/1295106 (Hg38)
End
1295221/1295106 (Hg38)
Orient
-
Location type
Intronic
Target gene
TERT
miRNAs that regulate target gene
hsa-mir-138-5p
;
hsa-mir-498
;
hsa-mir-193b-3p
;
hsa-mir-335-5p
;
hsa-mir-512-5p
;
hsa-mir-1207-5p
;
hsa-mir-1266-5p
;
hsa-mir-1182
;
hsa-mir-181a-5p
;
hsa-mir-6776-3p
;
hsa-mir-197-3p
;
hsa-mir-6740-3p
;
hsa-mir-6760-3p
;
hsa-mir-532-5p
;
hsa-mir-3064-5p
;
hsa-mir-422a
;
hsa-mir-346
;
hsa-mir-1226-3p
;
hsa-mir-1255a
;
hsa-mir-1255b-5p
;
hsa-mir-143-3p
;
hsa-mir-3161
;
hsa-mir-3605-5p
;
hsa-mir-3620-3p
;
hsa-mir-3682-3p
;
hsa-mir-4323
;
hsa-mir-4712-3p
;
hsa-mir-4733-3p
;
hsa-mir-4758-3p
;
hsa-mir-4770
;
hsa-mir-6088
;
hsa-mir-7112-3p
Nearest miRNA
hsa-mir-4635/Upstream/232132; hsa-mir-10397/Downstream/14204;
Nearest TSS
ENST00000502646/Upstream/37;
ENST00000605200/Downstream/26723;
Nearest CpG islands
chr5-CpG: 485/Target
, None/Upstream, None/Downstream
Nearest cancer related gene
TERT
(OG, No orient, 0)
Upstream sequence
GTCCTTGGATGTTTCTGTAAACCTTTGTTTTGAAATAATCCTAGATTCACAGtgcatgggtttcctgttgcttctgcaaatccccacacacttcatgcta
Downstream sequence
cccggagggggctgggccggggacccgggaggggtcgggacggggcggggtccgcgcggaggaggcggagctggaaggtgaaggggcaggacgggTGCCC
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Sample Information
×
Sample name
HX035_T01
Sample type
Tumor
Sample size
50mm
Age
68
Gender
Male
CpG Island Information
×
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