VISDB Viral Integration Site DataBase

VIS ID

TVIS10014650

Fusion event

HBV-SHOC2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1823

Orient

-

Integrated sequence

TAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGA

Chromosome

chr10

Cytoband

q25.2

Reference genome

Start

End

112718174/110958416 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-335-5p ; hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-92a-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-299-3p ; hsa-mir-20b-5p ; hsa-mir-491-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-575 ; hsa-mir-1825 ; hsa-mir-2110 ; hsa-mir-548t-5p ; hsa-mir-3189-5p ; hsa-mir-4668-5p ; hsa-mir-4676-5p ; hsa-mir-371b-3p ; hsa-mir-4758-3p ; hsa-mir-4786-3p ; hsa-mir-5699-5p ; hsa-mir-6124 ; hsa-mir-548az-5p ; hsa-mir-6796-5p ; hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-mir-15a-5p ; hsa-mir-98-3p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-379-3p ; hsa-mir-380-3p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-411-3p ; hsa-mir-1245a ; hsa-mir-3942-5p ; hsa-mir-4495 ; hsa-mir-4703-5p ; hsa-mir-6838-5p ; hsa-mir-8062 ; hsa-mir-8079 ; hsa-mir-5000-5p ; hsa-mir-216a-3p ; hsa-mir-218-5p ; hsa-mir-128-3p ; hsa-mir-4302 ; hsa-mir-4291 ; hsa-mir-3611 ; hsa-mir-3681-3p ; hsa-mir-7843-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-138-2-3p ; hsa-mir-5197-5p ; hsa-mir-219a-2-3p ; hsa-mir-4539 ; hsa-mir-219b-3p ; hsa-mir-4680-3p ; hsa-mir-203b-3p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-429 ; hsa-mir-4639-5p ; hsa-mir-488-5p ; hsa-mir-1245b-3p ; hsa-mir-5586-5p ; hsa-mir-1264 ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-4789-5p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-8485 ; hsa-mir-4731-3p ; hsa-mir-4801 ; hsa-mir-944 ; hsa-mir-6742-5p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-3151-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-3619-5p ; hsa-mir-761 ; hsa-mir-214-3p ; hsa-mir-922 ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-636 ; hsa-mir-4699-5p ; hsa-mir-3120-3p ; hsa-mir-127-5p ; hsa-mir-548au-3p ; hsa-mir-494-3p ; hsa-mir-34a-5p ; hsa-mir-34c-5p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-4519 ; hsa-mir-548e-5p ; hsa-mir-3942-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-342-3p ; hsa-mir-383-3p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-1228-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4284 ; hsa-mir-665 ; hsa-mir-633 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-4803 ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-1262 ; hsa-mir-1273g-3p ; hsa-mir-3160-3p ; hsa-mir-3664-5p ; hsa-mir-4252 ; hsa-mir-4487 ; hsa-mir-4522 ; hsa-mir-4701-3p ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-542-3p ; hsa-mir-558 ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-766-3p ; hsa-mir-7703

Nearest miRNA

hsa-mir-107/Upstream/60261; hsa-mir-202/Downstream/30510;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/38280, chr10-CpG: 317/Downstream/117816

Upstream sequence

gattcttctgcctcagcctcctgagtagctgggactacaggtgtgcaccaccacgcccagctaatttttgtatttttaatagagacggggtttcaccatg

Downstream sequence

ttggccaggatggtctcaatctcctgacctcctgatccgtctgcctcagcctcccaagatgctaggattacaggcgtgagccactgcacttggccCATCC