Basic Information
VIS ID
TVIS10014651
Fusion event
HBV-LOC105370283 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1801
Orient
+
Integrated sequence
CATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG| |TTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
82130234/81556099 (Hg38)
End
82130234/81556099 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105370283
Nearest miRNA
hsa-mir-1297/Upstream/3857983; hsa-mir-1267/Downstream/6062566;
Nearest TSS
ENST00000623511/Upstream/305661; ENST00000446314/Downstream/2326294;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/900789, chr13-CpG: 18/Downstream/2323430
Upstream sequence
TCATCTCTTAGAAAAAGTTTTGTCTTATAGGAAAAACTGAAATCGGCTTTATGTATCCTTTCTGAAATTAACTCAAATACTGATATCTCCAAAATTAGAT
Downstream sequence
TTGAAGGATTAAGAGACAGAAATGTGATAAATCAGCTTATCTTATAAGGCTGTTGGTGGTAACATTACAAAGTAAACAATAGAAACATTTGCTCTGTTGT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate