VISDB Viral Integration Site DataBase

VIS ID

TVIS10014652

Fusion event

HBV-SOX5 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

801

Orient

-

Integrated sequence

TCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTTTACCTCTATT| |ACCAATTTTCTTTTGTCTTTGGGTATACATTTGAACCCTAATAAAACCAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTGGG

Chromosome

chr12

Cytoband

p12.1

Reference genome

Start

End

24671602/24518668 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-194-5p ; hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-96-5p ; hsa-mir-130a-3p ; hsa-mir-181a-5p ; hsa-mir-132-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4766-5p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-574-5p ; hsa-mir-5580-3p ; hsa-mir-555 ; hsa-mir-374a-3p ; hsa-mir-136-3p ; hsa-mir-4704-5p ; hsa-mir-3529-3p ; hsa-mir-6759-5p ; hsa-mir-6793-5p ; hsa-mir-6748-5p ; hsa-mir-933 ; hsa-mir-4783-5p ; hsa-mir-3607-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/306173; hsa-let-7i/Downstream/1355352;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/1893389, chr12-CpG: 92/Downstream/43354

Upstream sequence

TGATTGACACTACTAGATAACACCCAAAACAGACTCAGGGCAAAAGAAAGTTGTTATCATAAGCACTTTTGTGATCCATTTATTCCCCTCTGTAAAATAG

Downstream sequence

GTAAGAGAATGCGCCAAGATATCACACATAGTCATTTACATACAGTATCATTTTATGGAATTTTCCAAGGTGTTAATTAAAAGTTTTAATGAATGTTAAT