VISDB Viral Integration Site DataBase

VIS ID

TVIS10014654

Fusion event

HBV-TCL1A integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2856

Orient

-

Integrated sequence

CTGTGGAAGGCTGGGATTCTATATAAGAGAGAGACTACACGCAGTGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAGCTACAGCATGGGAGGT| |TGGTCTTCCAAACCTCGACAAGGCATGGGGACAAATCTTTCTGTTCCCAATCCTCTGGGATTCTTTCCCGATCACCAGTTGGACCCAGCGTTCGGAGCCA

Chromosome

chr14

Cytoband

q32.13

Reference genome

Start

End

96181117/95714780 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29b-3p ; hsa-mir-181b-5p

Nearest miRNA

hsa-mir-1260a/Upstream/576794; hsa-mir-1185-1/Downstream/4394639;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/269, chr14-CpG: 151/Downstream/161092

Nearest cancer related gene

TCL1A(OG, No orient, 0)

Upstream sequence

GTTTTTTGGCAAAGGACAACTCCTGACGCTCCCTCTCCCTCTTCCATACACAAAGCATGCGTTTTCCACAGGTCTGATGTGCTGTGGACATCTAATAGCT

Downstream sequence

ATTACAAAATGGAGAATCATGGGTTTTTGCCCTTGGGCTTTGAGTTTACTAGTGAAAGCATAGTTCGAAATGAATACTTAAAAAGAAATCCCTCCTTCCA