Basic Information
VIS ID
TVIS10014658
Fusion event
HBV-MEF2C-AS1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
687
Orient
+
Integrated sequence
GAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCC| |ATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCC
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
88754904/89459087 (Hg38)
End
88754904/89459087 (Hg38)
Orient
-
Location type
Intronic
Target gene
MEF2C-AS1
Nearest miRNA
hsa-mir-10397/Upstream/792148; hsa-mir-103a-1/Downstream/557534;
Nearest TSS
ENST00000502646/Upstream/40280; ENST00000503691/Downstream/10952;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/569315, chr5-CpG: 17/Downstream/950439
Upstream sequence
CCCGCACAGGGTGGAGGGCAACCTCGGGGTCCAGGCACCTGGCTCCAAGCCTCGGACTGCAGAGCTAGGAGGCCCGACTTCCAGCCCAGCAGTAGAAGCC
Downstream sequence
ATCTTAATAGGTTTGTGATATTTTCAGTTCTGATTTTTAATATTTATTGCAATATGTTTTGTAAAATTCTAAAAATAAAGATAGATGAATTACCTACTGT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate