VISDB Viral Integration Site DataBase

VIS ID

TVIS10014662

Fusion event

HBV-chr1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

246

Orient

-

Integrated sequence

CACAGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAG| |TCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCT

Chromosome

chr1

Cytoband

p32.2

Reference genome

Start

End

57033100/56567427 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

LOC100288348 ; PLPP3

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-6883-3p ; hsa-mir-5192 ; hsa-mir-5186 ; hsa-mir-3120-5p ; hsa-mir-4502 ; hsa-mir-3162-3p ; hsa-mir-181b-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-4262 ; hsa-mir-185-5p ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-451b ; hsa-mir-2278 ; hsa-mir-4511 ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-195-5p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-138-2-3p ; hsa-mir-6809-3p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-4279 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6789-3p ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-5697 ; hsa-mir-1295b-3p ; hsa-mir-625-3p ; hsa-mir-562 ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6887-3p ; hsa-mir-122-3p ; hsa-mir-184

Nearest miRNA

hsa-mir-12136/Upstream/1341704; hsa-mir-101-1/Downstream/3165800;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/89430, chr1-CpG: 95/Downstream/11002

Upstream sequence

TCCAAATCTTCAGGAAAATTCTGGCATTGTTTCCCTTACATGTCTGCATTAATCTTAAGGTAtttcttttttttttttttttttttttgagatggagtct

Downstream sequence

cgctctgtcacccaggctggagtgcagtggcgcgatctcggctcactgcaagctctgcctcccgggttcatgccattctcctgcctcagcctcccacgta