AKAP9 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014664
Fusion event
HBV-AKAP9 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2741
Orient
-
Integrated sequence
TGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAAAACTAGG| |CATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAGC
Host Sequence
Chromosome
chr7
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
91671910/92042596 (Hg38)
End
91671910/92042596 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7E
Target gene
AKAP9
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-mir-10525/Upstream/16127327; hsa-mir-10399/Downstream/161419;
Nearest TSS
ENST00000635602/Upstream/1892; ENST00000491695/Downstream/15030;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/101562, chr7-CpG: 115/Downstream/91185
Nearest cancer related gene
AKAP9(OG, No orient, 0)
Upstream sequence
TTTTCCTGTGTTTGCATTTCAGAGGGAGGAAAGTGAGTTTGTGTTAAATCATATACTTTATGGATGTGTCTGTGCTTGCTACTCCAGGCAGGAGGTAAAT
Downstream sequence
GACATGCTGTTTCCAAGTTGACAGGTTTTCTTTCTGTCTTCTCCTCTCTTCCTTTACACAAACTTAAACAGAATGGAAATGAAAACCAAGGAGAAGTTGA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
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