VISDB Viral Integration Site DataBase

VIS ID

TVIS10014666

Fusion event

HBV-RBM33 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2021

Orient

+

Integrated sequence

GAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGG| |CCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAG

Chromosome

chr7

Cytoband

q36.3

Reference genome

Start

End

155443949/155651255 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-106b-3p ; hsa-mir-20a-3p ; hsa-mir-221-3p ; hsa-mir-34a-5p ; hsa-mir-33a-5p ; hsa-mir-570-3p ; hsa-mir-586 ; hsa-mir-33b-5p ; hsa-mir-510-3p ; hsa-mir-934 ; hsa-mir-3618 ; hsa-mir-5096 ; hsa-mir-3912-5p ; hsa-mir-6749-3p ; hsa-mir-6802-3p ; hsa-mir-6753-3p ; hsa-mir-7107-3p ; hsa-mir-3667-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-5088-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-1292-5p ; hsa-mir-1972 ; hsa-mir-4502 ; hsa-mir-5586-3p ; hsa-mir-759 ; hsa-mir-8075

Nearest miRNA

hsa-mir-10399/Upstream/4217616; hsa-mir-153-2/Downstream/1923081;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/6132, chr7-CpG: 19/Downstream/129653

Upstream sequence

TCACTCCCTGTTGGCTCATGGAGCCCAGAGGTAGAGCCCCAGGAAGCCACACCAGGGGACCTAAGTTGTCACCAGATGAAATCTATCTGACATCCTAGGA

Downstream sequence

cacaacttgattggtggttttgttgggtccagaattttagatttgagtttatttttgtaagatttttggcggtattgttgtgttttctggcatccagatc