VISDB Viral Integration Site DataBase

VIS ID

TVIS10014667

Fusion event

HBV-RBM33 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1634

Orient

+

Integrated sequence

TTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAG| |GTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGG

Chromosome

chr7

Cytoband

q36.3

Reference genome

Start

End

155444002/155651308 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-106b-3p ; hsa-mir-20a-3p ; hsa-mir-221-3p ; hsa-mir-34a-5p ; hsa-mir-33a-5p ; hsa-mir-570-3p ; hsa-mir-586 ; hsa-mir-33b-5p ; hsa-mir-510-3p ; hsa-mir-934 ; hsa-mir-3618 ; hsa-mir-5096 ; hsa-mir-3912-5p ; hsa-mir-6749-3p ; hsa-mir-6802-3p ; hsa-mir-6753-3p ; hsa-mir-7107-3p ; hsa-mir-3667-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-5088-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-1292-5p ; hsa-mir-1972 ; hsa-mir-4502 ; hsa-mir-5586-3p ; hsa-mir-759 ; hsa-mir-8075

Nearest miRNA

hsa-mir-10399/Upstream/4217669; hsa-mir-153-2/Downstream/1923028;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/6185, chr7-CpG: 19/Downstream/129600

Upstream sequence

atatcacaccactgcactccagcctgggcaacagaatgagactctgtcgccaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaGGGGGGTTTT

Downstream sequence

tttgtaagatttttggcggtattgttgtgttttctggcatccagatctgctcttgagaagtttgaggacattctgattcctaatcattttttatgtgacc