Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014671
Fusion event
HBV-FRAS1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1809
Orient
+
Integrated sequence
AAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATT
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
Start
End
79048008/78126854 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/1551228; hsa-mir-1243/Downstream/4626483;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/67598, chr4-CpG: 34/Downstream/54892
Upstream sequence
ATCATGTAATAAGTGAGAGGACAAAGGAAGAAAGTGTTATTGATATAGAGTACCATTAACCAACTTTGTGTGTATATGTGTACCTCTAGAATAGATTTAT
Downstream sequence
TTTGTTTTAGTCAGTTTTTGTTCCAATTACAAGCAGATTAGTGGAACCTTGATGTGATAGCCTGAAGATAATGAAGTCACTCAGAATAAGCCCCAACCAT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.