Basic Information
VIS ID
TVIS10014673
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AB033550.1
Start
1489
Orient
-
Integrated sequence
GCTGCCAACTGGATCCTTCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGGCTCTATCGTC| |CCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGC
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh37/hg19
Start
68664016/67954124 (Hg38)
End
68664016/67954124 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/10563912; hsa-mir-10524/Downstream/3422836;
Nearest TSS
ENST00000381078/Upstream/64785; ENST00000449928/Downstream/101227;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1859186, chr6-CpG: 37/Downstream/680716
Upstream sequence
ATTATGAAATGTTTAAAGAAAAATTAAGTGACTAGGATGAGAAAAGATAATATTTAACATATACACATGAAATAATAAACAACATGTACTGGATGAGAGT
Downstream sequence
TTACTTTTTTCTACAACTGCAAGCTGTTTCTCAGCCTAAGGAGATTTCTTTAGGCTGAGAGCTATCAAGAGTTGAAAATGAATTAAGCCCCATCCCCTGG
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate