Basic Information
VIS ID
TVIS10014676
Fusion event
HBV-chr7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1823
Orient
+
Integrated sequence
TAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGA
Host Sequence
Chromosome
chr7
Cytoband
q35
Reference genome
GRCh37/hg19
Start
145783086/146085993 (Hg38)
End
145783086/146085993 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10399/Upstream/2703193; hsa-mir-153-2/Downstream/1292024;
Nearest TSS
ENST00000635602/Upstream/404624; ENST00000637105/Downstream/30009;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1249833, chr7-CpG: 70/Downstream/30189
Upstream sequence
atttgacaaaatccagcaacattttattattaaaaccctcagcaaaattggcataaaagggacataacttaatgtaattaaagccatctatgacaaaccc
Downstream sequence
ATTGCTCCTAGCAATAAGGTATTGAAATTGTATTTGGTACTTAGTTTTCCTTTTATTGTTTTTAATAGTCCCTTCACTTTGATTCCAAAACTATTGGTTA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate