Basic Information
VIS ID
TVIS10014677
Fusion event
HBV-LINC00587 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1820
Orient
-
Integrated sequence
GTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAA
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
105333812/102571530 (Hg38)
End
105333812/102571530 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC00587
Nearest miRNA
hsa-let-7a-1/Upstream/4342313; hsa-mir-12126/Downstream/4029398;
Nearest TSS
ENST00000422679/Upstream/51894; ENST00000612124/Downstream/423781;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/832736, chr9-CpG: 38/Downstream/1427819
Upstream sequence
atgcatacatcacaaagaagtttgtctgaatgcttctttgtagtttttatttcaagatatttccttttgcaccacagggctcaaagggctccaaatatcc
Downstream sequence
gctgtaagtgcttgtatcagaaaaatgaaaaatttcaaattagcaagtcaattatgcatcttaaagaactagaaaagcaagagcaagccaaacccagaat
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate