Basic Information
VIS ID
TVIS10014679
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
D00329.1
Start
816
Orient
+
Integrated sequence
CCACTGTCTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTATGCCGCTGTTACCAATTTTCTTTTG| |TCTTTGGGTATACATTTAAACCCTAACAAAACAAAAAGATGGGGATATTCCCTTAACTTCATGGGATATGTAATTGGGAGTTGGGGCACATGGCCACAGG
Host Sequence
Chromosome
chr8
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
52216280/51303720 (Hg38)
End
52216280/51303720 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-124-1/Upstream/8407445; hsa-mir-10400/Downstream/10411068;
Nearest TSS
ENST00000518652/Upstream/46032; ENST00000521612/Downstream/36465;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1393420, chr8-CpG: 98/Downstream/104882
Upstream sequence
CATTAACCAATGCACAGTAAATTACCAATGCACAGTAAATTAGGAAATAAATATGATAGTAAAGCAATCATATGATGAAAGTCACATGGGATTCTCCAAA
Downstream sequence
cattcgttctgggttctcttcctattttcgccattttgagtgatcttacgcacatcatttaatgttactaagcctcagttttttcaactgcaaaatgacc
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate