VISDB Viral Integration Site DataBase

VIS ID

TVIS10014681

Fusion event

HBV-CDK15 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1603

Orient

+

Integrated sequence

CCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACG| |TCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCA

Chromosome

chr2

Cytoband

q33.1

Reference genome

Start

End

202750060/201885337 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-147a ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-6867-5p ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6782-5p ; hsa-mir-876-3p ; hsa-mir-323a-5p

Nearest miRNA

hsa-mir-10b/Upstream/12752226; hsa-mir-1244-1/Downstream/4897897;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/103905, chr2-CpG: 334/Downstream/147326

Upstream sequence

TGAATGCTTCCACGTAATTTCAAACCTATTCTGTTTATTGGTTTTTTTGTGTATTCTATTCAAAGTTGAACCAGAATATTTTGTCATTCTATGAGGCCAG

Downstream sequence

GTTTCAGGGGCTGGGGATGTTGGAAAAGAGGGAGGGAAGATTCTCAGCCATCCTCTTGACTCTGTGCTACTTCTAGGAGTTTGTAACGTAACTCAGACCA