Basic Information
VIS ID
TVIS10014683
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
D00330.1
Start
1040
Orient
-
Integrated sequence
TGTGGTTTAGGAAACTTCCTGTAAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGGTTTGCCGCCCCTTTCACGCAATGTGG| |ATATCCTGCTTTAATGCCTTTATATGCATGTATACAAGCAAAACAGGCTTTTACTTTCTCGCCAACTTACAAGGCCTTTCTAACTAAACAGTATCTGAAC
Host Sequence
Chromosome
chr4
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
180753995/179832842 (Hg38)
End
180753995/179832842 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/5408978; hsa-mir-1305/Downstream/2336451;
Nearest TSS
ENST00000502981/Upstream/367537; ENST00000512480/Downstream/926196;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2390288, chr4-CpG: 160/Downstream/225043
Upstream sequence
ctgggcgacagagcgagactccgtctcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaag
Downstream sequence
caaaaacaaggatggtaataattacaagtatctctttcttattttatatgattatgttgtatatattataaacaactgctttgcttatcctacttttact
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate