Basic Information
VIS ID
TVIS10014684
Fusion event
HBV-LOC105375630 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
D00330.1
Start
1829
Orient
+
Integrated sequence
GTGGGAGGAGTTGGGGGAGGAGGTTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTGTGTTCACCAGCACCATGCAACTTTTTCACC| |TCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGG
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
89649912/88637683 (Hg38)
End
89649912/88637683 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105375630
Nearest miRNA
hsa-mir-12123/Upstream/8396210; hsa-mir-10400/Downstream/2567802;
Nearest TSS
ENST00000518652/Upstream/95066; ENST00000521936/Downstream/62608;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/309431, chr8-CpG: 92/Downstream/1119624
Upstream sequence
CATTTTGTTTTCACTGTCTCAACAAAGCCCTTTTCATATAGAAAATTGATCCTTAATGTCGTTGGTAACACACTGATGGAAATAAAAGTATGCTGTGGCA
Downstream sequence
ccaagtgctggccggccaccatgcatgcagttaacccaccccaaggaaaaaaatcaagggaggagaaacagaagccccagaaccatgccaatgtgtgaaa
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate