VISDB Viral Integration Site DataBase

VIS ID

TVIS10014687

Fusion event

HBV-HSPA8 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1819

Orient

+

Integrated sequence

TGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATA

Chromosome

chr11

Cytoband

q24.1

Reference genome

Start

End

122939930/123069222 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-877-5p ; hsa-mir-151a-5p ; hsa-mir-130b-5p ; hsa-mir-615-3p ; hsa-mir-324-3p ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-15b-5p ; hsa-mir-10a-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-25-3p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-3692-3p ; hsa-mir-587 ; hsa-mir-448 ; hsa-mir-106a-3p ; hsa-mir-6868-3p ; hsa-mir-6826-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-340-5p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-1914-5p ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-338-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-519d-3p ; hsa-mir-106a-5p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-33a-5p ; hsa-mir-105-5p ; hsa-mir-1297 ; hsa-mir-15a-5p ; hsa-mir-195-5p ; hsa-mir-205-5p ; hsa-mir-26b-5p ; hsa-mir-3064-3p ; hsa-mir-32-3p ; hsa-mir-33a-3p ; hsa-mir-365a-3p ; hsa-mir-365b-3p ; hsa-mir-3671 ; hsa-mir-424-5p ; hsa-mir-4272 ; hsa-mir-4307 ; hsa-mir-4461 ; hsa-mir-4465 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-497-5p ; hsa-mir-503-5p ; hsa-mir-5089-3p ; hsa-mir-5697 ; hsa-mir-580-3p ; hsa-mir-6074 ; hsa-mir-607 ; hsa-mir-625-3p ; hsa-mir-646 ; hsa-mir-6509-5p ; hsa-mir-6838-5p ; hsa-mir-7853-5p ; hsa-mir-802

Nearest miRNA

hsa-let-7a-2/Upstream/916914; hsa-mir-3167/Downstream/312218;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/6127, chr11-CpG: 115/Downstream/125496

Upstream sequence

ccgtcgctactaaaaatacaaaaaattagccaggcgtggtggcaggcgcctgttgtcccaggtactcgggtggctgaggcaggagaatggcgtgaacccg

Downstream sequence

ggaggcggagcttgcagtgagctgagattgtgccactgcactccagcctgggcgacaaagctagactcggtctcaaaataaaaataaaagtgaaaataaa