Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014689
Fusion event
HBV-HEATR6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
809
Orient
+
Integrated sequence
CTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTTTACCTCTATTACCAATTT| |TCTTTTGTCTTTGGGTATACATTTGAACCCTAATAAAACCAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTGGGGTACTTTA
Host Sequence
Chromosome
chr17
Cytoband
q23.1
Reference genome
Start
End
58157689/60080328 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10226/Upstream/37223; hsa-mir-1250/Downstream/2863887;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/1262, chr17-CpG: 164/Downstream/39185
Upstream sequence
AAGACTTTGGGCTTGGGGAGAAATGTTAATTTTTTTGTTTGGATTTAGATTCCGTTGTGCTGGTATATTATTTCTTATTCCTAgtctgtgtacatatgtg
Downstream sequence
cgttatatatgtgcatgtgtgtgtgtgtattcgtgtAAAGAAATGTATTCAAGCATTTGTTCAGAGAAGATCAGGAGCTGAAACCTAGTCGTTGGAtatt
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.