Basic Information
VIS ID
TVIS10014691
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
364
Orient
-
Integrated sequence
TTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCT| |GGCTATCGCTGGATGTGTCTGCGGCGTTTTATCATATTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGT
Host Sequence
Chromosome
chr5
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
173175423/173748420 (Hg38)
End
173175423/173748420 (Hg38)
Orient
+
Fragile sites / regions
FRA5G
Nearest miRNA
hsa-mir-10397/Upstream/400884; hsa-mir-1229/Downstream/1003314;
Nearest TSS
ENST00000502646/Upstream/2209; ENST00000518141/Downstream/39993;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/131528, chr5-CpG: 23/Downstream/139508
Nearby gene
LINC01484(-2211) ;
Upstream sequence
CCACGTGCGCAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAgggcggggccgcggaaaggaaggggaggggctgggagggcccggagggg
Downstream sequence
caggaagcagacactgagacaatgatttggggcaaggtttttatttggaaggtgaccccaggcatcttggtgagagactagggaagtgacacagggaaca
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate