Basic Information
VIS ID
TVIS10014697
Fusion event
HBV-LOC105378887 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1849
Orient
+
Integrated sequence
AGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGT| |TCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCT
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
106996329/106453707 (Hg38)
End
106996329/106453707 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105378887
Nearest miRNA
hsa-mir-101-1/Upstream/6172399; hsa-mir-11399/Downstream/1443516;
Nearest TSS
ENST00000473358/Upstream/372546; ENST00000415910/Downstream/364532;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/372475, chr1-CpG: 104/Downstream/602876
Upstream sequence
agatcaaatatcaattccagatagcccagagccattacagagaacacttccaaaaagtttttttttcccctggaacTTTTTCTAATATGAATTTCTCTAT
Downstream sequence
AATTTGCAgttcagtcagagaagtagaaccactgagttatataataaagggctaattatagggaatccaccatatgcaattgtgagtactatagaaagtt
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate