VISDB Viral Integration Site DataBase

VIS ID

TVIS10014703

Fusion event

HBV-PUM1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1831

Orient

-

Integrated sequence

GGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTC| |TGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAG

Chromosome

chr1

Cytoband

p35.2

Reference genome

Start

End

31503626/31030779 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-423-3p ; hsa-mir-151a-3p ; hsa-mir-181a-5p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-296-3p ; hsa-mir-324-3p ; hsa-mir-324-5p ; hsa-mir-186-5p ; hsa-mir-99a-5p ; hsa-mir-568 ; hsa-mir-508-3p ; hsa-mir-219a-5p ; hsa-mir-4445-5p ; hsa-mir-4782-3p ; hsa-mir-6766-3p ; hsa-mir-142-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-340-5p ; hsa-mir-6809-5p ; hsa-mir-7112-5p ; hsa-mir-4708-3p ; hsa-mir-651-3p ; hsa-mir-99b-3p ; hsa-mir-99a-3p ; hsa-mir-335-3p ; hsa-mir-4528 ; hsa-mir-4283 ; hsa-mir-760 ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-3149 ; hsa-mir-5004-3p ; hsa-mir-3618 ; hsa-mir-4696 ; hsa-mir-571 ; hsa-mir-451b ; hsa-mir-4704-5p ; hsa-mir-548e-5p

Nearest miRNA

hsa-mir-12136/Upstream/291547; hsa-mir-101-1/Downstream/727881;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/121660, chr1-CpG: 60/Downstream/34786

Upstream sequence

tagcctgggtgagagtgagacagtgtccggaaaaaaaaaaaaGGATTTAATAACATGCTGCCTAGCTGCCTATACATTATATCACCTAAGAATCTTAACT

Downstream sequence

GTCAGAACTAACACTGCAAAAAGATACAGTTGCATTATTGTTTTCAGTCACATATTTTAAAAACGCACAGCCAATACTATGCTACAAATGAGACACACCG