Basic Information
VIS ID
TVIS10014706
Fusion event
HBV-LOC100289080 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1862
Orient
-
Integrated sequence
GGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTG| |TTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTC
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
87553687/87842795 (Hg38)
End
87553687/87842795 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11F
Target gene
LOC100289080
Nearest miRNA
hsa-mir-10392/Upstream/1564397; hsa-let-7a-2/Downstream/333707;
Nearest TSS
ENST00000527297/Upstream/123384; ENST00000532849/Downstream/207311;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/804744, chr11-CpG: 45/Downstream/332280
Upstream sequence
GACTTTCCTGGAAAGACTACCTCAGAATACACAAGTGCACCTCACTAGCCAAAATAAATCCCCACCCCATGCGcacacatacacacatgcatgcgcatgc
Downstream sequence
acacacacacacacgcgcgcgcacacacacacacacacacacacacacacaAATCCCTTTTTATAAAAAATGTTTGAGAAACAAAAAACATTTTTTATAA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate