VISDB Viral Integration Site DataBase

VIS ID

TVIS10014713

Fusion event

HBV-HS6ST3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1794

Orient

+

Integrated sequence

CTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAAT| |TGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTT

Chromosome

chr13

Cytoband

q32.1

Reference genome

Start

End

96965850/96313596 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-5589-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-574-5p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-592 ; hsa-mir-513a-5p ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-597-5p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-4445-5p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-6767-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485

Nearest miRNA

hsa-mir-1297/Upstream/3823376; hsa-mir-1267/Downstream/113633;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/221688, chr13-CpG: 35/Downstream/680544

Upstream sequence

TCATTTTGTCTTAGACAATTCTCATTTACGTATCTTAGGTCATGCAGTTCTTTTCCACTTACCTTCAATGGTGTCTTCCCTCTTCTTGCCCATTTTCCTA

Downstream sequence

AATGCTGTAGATTCATCCCAAGTCTACTACAAATGTAATGTCCCCCATGATAGCCTCAGATATTCTGTTCCTCACTGATGTGTTTCATTTCTGAATTCCT