Basic Information
VIS ID
TVIS10014715
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2052
Orient
-
Integrated sequence
TTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCA| |CCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATTTGGAAGACCCAGCATCCAGGGAATTA
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
14634042/14730725 (Hg38)
End
14634042/14730725 (Hg38)
Orient
+
Fragile sites / regions
FRA17A
Nearest miRNA
hsa-mir-1253/Upstream/1187079; hsa-mir-10226/Downstream/520902;
Nearest TSS
ENST00000595228/Upstream/4996; ENST00000445035/Downstream/49478;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/385321, chr17-CpG: 77/Downstream/529888
Upstream sequence
ggattacaggcgtgagccaccattcctggcctggagaaataacttgatccaggggtatcgcaggaaagtacaagatgagtctgaaatatcatgccaggaa
Downstream sequence
gtgaagaggagtttgaagaatcagggacacatatcaaaaggggcaggagcctgcttgcaggatccccctggccaaagcagaacaagctgagcaccaaaat
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate