Basic Information
VIS ID
TVIS10014722
Fusion event
HBV-chr15 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1944
Orient
-
Integrated sequence
CATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTT| |ACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGT
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
37994979/37702778 (Hg38)
End
37994979/37702778 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1233-1/Upstream/729877; hsa-mir-10393/Downstream/3988807;
Nearest TSS
ENST00000557528/Upstream/211970; ENST00000560841/Downstream/219161;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/211858, chr15-CpG: 36/Downstream/370016
Upstream sequence
GTATTACTCATACCCTCCTGGTCTGGTGATAAAAACTAAAGAAAGGAACTTATCCAGGGATCTAAGCCATGTTTTCCTCTCCTATAATGAACACAAGCTC
Downstream sequence
ACTTGTCTGTCAGGAAAACCAGCACCCTTCAGCCTTAATATTGACTTGAACCTCAGTCAGATCAAGTCCAACCAAAGAGTGCCAGAATCACATATTCACA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate