VISDB Viral Integration Site DataBase

VIS ID

TVIS10014724

Fusion event

HBV-RB1CC1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2625

Orient

-

Integrated sequence

TGGCAAACTCCCTCCTTTCCTAACATTCATTTACAGGAGGACATTATTAATAGATGTGAACAATATGTGGGCCCTCTTACAACTAATGAAAAAAGGAGAT| |TAAAATTAATTATGCCTGCTAGGTTTTATCCTAACCTTACCAAATACTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCA

Chromosome

chr8

Cytoband

q11.23

Reference genome

Start

End

53617385/52704825 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-133b ; hsa-mir-375 ; hsa-mir-98-5p ; hsa-mir-193b-3p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-224-3p

Nearest miRNA

hsa-mir-124-1/Upstream/9808550; hsa-mir-10400/Downstream/9009963;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/138758, chr8-CpG: 153/Downstream/8620

Nearest cancer related gene

RB1CC1(TSG, No orient, 0)

Upstream sequence

CAAGCCAAGAAAGGCCTAAGTCACTGATGTTAGATTTAAAGCTTTAATTAAATTCAATTAATCATCTTTTACTAATACCTCCTTAAATAGCCTATGTTGC

Downstream sequence

ACATAAGTATTACTTTTCACCAAATAGTCACGATTTCCTAAAATCTGACTTGATGCTCATTTTATATAAAGTCCTTCTTAACTTTTATAAAATGAAACCA