Basic Information
VIS ID
TVIS10014726
Fusion event
HBV-PANTR1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1680
Orient
+
Integrated sequence
GCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAA| |TGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGG
Host Sequence
Chromosome
chr2
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
105457561/104841103 (Hg38)
End
105457561/104841103 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
PANTR1
Nearest miRNA
hsa-mir-1285-2/Upstream/2408737; hsa-mir-10b/Downstream/4300387;
Nearest TSS
ENST00000437798/Upstream/83384; ENST00000361360/Downstream/14408;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/181621, chr2-CpG: 210/Downstream/1612
Upstream sequence
ATGTTATATGCAAATGTATTCAGTTGGGGtatgtatatattttgttatgttatgtacataaacatctacccttgtgcatatgtatatttacatcatgtat
Downstream sequence
aaatatgtgtagtatatTACCAAACTGTACTATACTTAAGGAGGAGGAGGAGCTTCCAAGGATTGCCATACAATATTTTAGTTAACTGAGTACTGTTTCC
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate