VISDB Viral Integration Site DataBase

VIS ID

TVIS10014727

Fusion event

HBV-CCNA2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1817

Orient

+

Integrated sequence

TTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTA

Chromosome

chr4

Cytoband

q27

Reference genome

Start

End

122742221/121821066 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-let-7b-5p ; hsa-mir-146a-5p ; hsa-mir-193b-3p ; hsa-mir-132-3p ; hsa-mir-212-3p ; hsa-mir-98-5p ; hsa-mir-197-3p ; hsa-mir-10b-3p ; hsa-mir-130b-3p ; hsa-mir-27b-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1825 ; hsa-mir-4676-5p ; hsa-mir-575 ; hsa-mir-548e-5p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-4295 ; hsa-mir-130a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-301a-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-6835-3p ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-22-3p

Nearest miRNA

hsa-mir-12113/Upstream/7164212; hsa-mir-1305/Downstream/3686193;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/19463, chr4-CpG: 71/Downstream/2336

Upstream sequence

CAAATGATGTCAATCCTTGATGTCAATCCTTACACCTACCTCTGCTCTTTGCTGCAGAACCTTAGGTTATTTCCCAGTTTCTCTGCATTATGCCAGTAAA

Downstream sequence

GACATGTCCATAGTATGTGGTGACTCTGGGACAATTCAAAAGATATGATTAAATTAATTGTTTGCCTATTTAGTTTAATAGCTAAAAATGACTGCCATGG