VISDB Viral Integration Site DataBase

VIS ID

TVIS10014728

Fusion event

HBV-CCNA2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1639

Orient

-

Integrated sequence

GCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTT| |GCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAG

Chromosome

chr4

Cytoband

q27

Reference genome

Start

End

122742581/121821426 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-let-7b-5p ; hsa-mir-146a-5p ; hsa-mir-193b-3p ; hsa-mir-132-3p ; hsa-mir-212-3p ; hsa-mir-98-5p ; hsa-mir-197-3p ; hsa-mir-10b-3p ; hsa-mir-130b-3p ; hsa-mir-27b-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1825 ; hsa-mir-4676-5p ; hsa-mir-575 ; hsa-mir-548e-5p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-4295 ; hsa-mir-130a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-301a-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-6835-3p ; hsa-mir-29c-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-22-3p

Nearest miRNA

hsa-mir-12113/Upstream/7164572; hsa-mir-1305/Downstream/3685833;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/19823, chr4-CpG: 71/Downstream/1976

Upstream sequence

CATATATTCATATTTTAAATATAGTTTTAAATTCTGACAGTATTTAATCATACTATGGAAAAAGTGTCTAAGATACAAATAATACATAAATGTGTTAATC

Downstream sequence

TTTAAAATCCAAGTTTTGAGATAATATCTAAGATTTGTCCCAAGAGAAACTGCAGATCCCAGAGTCTGACATATATAAAGCACAAGTAGGCAATAGCTAG