VISDB Viral Integration Site DataBase

VIS ID

TVIS10014730

Fusion event

HBV-THSD4 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1820

Orient

-

Integrated sequence

GTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAA

Chromosome

chr15

Cytoband

q23

Reference genome

Start

End

71645717/71353378 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-1909-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-512-3p ; hsa-mir-6768-3p ; hsa-mir-4484 ; hsa-mir-548an ; hsa-mir-4665-5p ; hsa-mir-4472 ; hsa-mir-1275 ; hsa-mir-4447 ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6825-5p ; hsa-mir-7160-5p ; hsa-mir-6853-5p ; hsa-mir-6087 ; hsa-mir-4649-3p ; hsa-mir-1827 ; hsa-mir-670-5p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-6882-3p ; hsa-mir-1908-5p ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-4312 ; hsa-mir-637 ; hsa-mir-6852-5p ; hsa-mir-6791-5p ; hsa-mir-4308 ; hsa-mir-4292 ; hsa-mir-4438 ; hsa-mir-3925-3p ; hsa-mir-4709-3p ; hsa-mir-665 ; hsa-mir-6863 ; hsa-mir-766-3p ; hsa-mir-873-5p

Nearest miRNA

hsa-mir-10393/Upstream/1273910; hsa-mir-11181/Downstream/1233839;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/138021, chr15-CpG: 18/Downstream/458473

Upstream sequence

CATCTTTAGCTGGTTTGGGCCAAGTGTAATTGTTTGATAAACAAGGCATGTGGATAAAAATTGTGTCCACTTTTTATTAGCAAACACTTAATCTGATTGC

Downstream sequence

AAAAGAAACCATCATGTGATTCAGCTTTTTCACAGTTTGCTTTACTAGAGCAAGTCAGAGCAGATGAGAAAGAACACCTAAACTGTGGTTTCCTTTAAAG