Basic Information
VIS ID
TVIS10014732
Fusion event
HBV-chr19 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2495
Orient
-
Integrated sequence
CGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATCCCTTGGACTCATAAGGTGGGAAACTTTACTGGGCTTTAT| |TCTTCTACTGTACCTGTCTTTAATCCTGAGTGGCAAACTCCCTCCTTTCCTAACATTCATTTACAGGAGGACATTATTAATAGATGTCAACAATATGTGG
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
33771843/33280937 (Hg38)
End
33771843/33280937 (Hg38)
Orient
+
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/12881583; hsa-let-7e/Downstream/1841763;
Nearest TSS
ENST00000633603/Upstream/55087; ENST00000589932/Downstream/4802;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/44743, chr19-CpG: 302/Downstream/20218
Nearby gene
LOC111365153(-4696) ;
Upstream sequence
ATGCCCATCCCGGCAAACCTGCAGGGCCCTTGATTGTAAGTCACCCCACTCACCCCGGGCTGCTTCTCACCACTGTTTCCTGTGCTGAAGTGGGAGTCCA
Downstream sequence
GACCCCCAAGAACCAGGATCCAGGGTCACTGATCACCAGGTCACCAGGGGCAGCTCCTACAGGCCTGGGGTCTGCCTGCGCTTCCTGTCGGGGATGGTGG
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate