VISDB Viral Integration Site DataBase

VIS ID

TVIS10014737

Fusion event

HBV-chr1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1645

Orient

+

Integrated sequence

TCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAA| |GGTCTTACATAAGAGGACTCTTGGACTCTCATCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGG

Chromosome

chr1

Cytoband

q23.3

Reference genome

Start

End

161091640/161121850 (Hg38)

Orient

-

Location type

Intronic

Target gene

DEDD ; NIT1 ; PFDN2

miRNAs that regulate target gene

hsa-mir-224-5p ; hsa-mir-193b-3p ; hsa-mir-24-3p ; hsa-mir-935 ; hsa-mir-93-3p ; hsa-mir-615-3p ; hsa-mir-615-3p ; hsa-mir-210-3p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-3919 ; hsa-mir-6504-3p ; hsa-mir-338-5p ; hsa-mir-5692a ; hsa-mir-3613-3p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p

Nearest miRNA

hsa-mir-101-1/Upstream/1221771; hsa-mir-1182/Downstream/105336;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/3528, chr1-CpG: 52/Downstream/37498

Upstream sequence

GTTTTTTAGACAAAATTTAAGAGCTCTCATAAAGCCAGAAGTATTGATAACTCCTTAGTGCATCCAAAAAAAAGTGTTCACATCAATCCCTTACAAAGAC

Downstream sequence

TATGTGCTGTAGACTTTGCTTCTTCCTATACATTTGTCTTACGGCTCAGTGGTAAGGTAGCTGTAGAGACACATTACGGGGTAAATGGAAAAGGGAAATA