VISDB Viral Integration Site DataBase

VIS ID

TVIS10014741

Fusion event

HBV-RGS12 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2416

Orient

-

Integrated sequence

CTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGT| |CGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATCCCTTGGACTCATAAGGTGGGAAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTT

Chromosome

chr4

Cytoband

p16.3

Reference genome

Start

End

3421893/3420166 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-149-5p ; hsa-mir-138-5p ; hsa-mir-7704 ; hsa-mir-4532 ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459

Nearest miRNA

hsa-mir-4800/Upstream/1170010; hsa-mir-12113/Downstream/2503109;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/6540, chr4-CpG: 24/Downstream/27757

Upstream sequence

acaacagacattggggcctatttaaagatggagggtaggacagggtttttcgtagggacagggtttttccatgttgccaggaaaggcaaggattgaaaaa

Downstream sequence

GGTCTGGAGGCCGCATCCGGCTGAGAGCGCTGGCTGTTGCCACAGTTGGGGGTTTCCAGTTAGGCCCAGAAACTACATTTGGGGATGAAAGCTCCAGATG