Basic Information
VIS ID
TVIS10014742
Fusion event
HBV-chr7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1873
Orient
-
Integrated sequence
TAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCC| |AAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTC
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
71198387/71733402 (Hg38)
End
71198387/71733402 (Hg38)
Orient
+
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/425632; hsa-mir-10399/Downstream/964501;
Nearest TSS
ENST00000635602/Upstream/397853; ENST00000434423/Downstream/77093;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/600006, chr7-CpG: 187/Downstream/602370
Upstream sequence
caggtatggtgatgcacaccggtagttccagctgcccaggagactgaggtgggaggatcacctgagcctgaagaagtcaaggctgaagtgagctgtgatt
Downstream sequence
CCCGCGCGGGAGCTCAGCTGGGAAGCCGGGCTCTGAAGACCGATGCTCTAGCGCCCCCTGCTGGCGCCTGGCCTTGATTCCGCTGCTTCCTTTCCCCTGA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate