VISDB Viral Integration Site DataBase

VIS ID

TVIS10014749

Fusion event

HBV-SOX5 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

672

Orient

+

Integrated sequence

CAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGCT| |CAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTAC

Chromosome

chr12

Cytoband

p12.1

Reference genome

Start

End

23811547/23658613 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-194-5p ; hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-96-5p ; hsa-mir-130a-3p ; hsa-mir-181a-5p ; hsa-mir-132-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4766-5p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-574-5p ; hsa-mir-5580-3p ; hsa-mir-555 ; hsa-mir-374a-3p ; hsa-mir-136-3p ; hsa-mir-4704-5p ; hsa-mir-3529-3p ; hsa-mir-6759-5p ; hsa-mir-6793-5p ; hsa-mir-6748-5p ; hsa-mir-933 ; hsa-mir-4783-5p ; hsa-mir-3607-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/5985219; hsa-let-7i/Downstream/553808;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/1033334, chr12-CpG: 92/Downstream/903409

Upstream sequence

AGGATCTCCCAAAGTCATCGGTTTATAAACTTCTGGGAAGGCAGAGGAGAGGGGAAGAGCTGGTCACAATAATTCTAACACAAAAAATACAGAAACCAgc

Downstream sequence

tgggcatggtggctcatgccttaatcctaacactttgggaggccaagatgggtggatcacttgaggtaggagttcgaaaccaggctggccaacatggtga