VISDB Viral Integration Site DataBase

VIS ID

TVIS10014750

Fusion event

HBV-chr16 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2026

Orient

-

Integrated sequence

TGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTA| |GAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATT

Chromosome

chr16

Cytoband

q22.2

Reference genome

Start

End

72095254/72061355 (Hg38)

Orient

-

Location type

Intronic

Target gene

HP ; HPR

miRNAs that regulate target gene

hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-4436b-5p ; hsa-mir-4290 ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-1247-5p ; hsa-mir-6777-3p ; hsa-mir-483-3p

Nearest miRNA

hsa-mir-1225/Upstream/2030933; hsa-mir-11401/Downstream/4807581;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/52366, chr16-CpG: 15/Downstream/31875

Upstream sequence

TAactgttgtccttgttttacagacaaggaaacagagactcagagatggtaagtgagttgcttaaggttacatagctatgaaacagggaagcagaacttt

Downstream sequence

gaacccaggtctgtttgatacaaactcagaggtcctttcactgcatgctgttgcctcctcAAAGTGAATTAGGAGAAAAGGCATGGGCCTGGTTGAGGAA