VISDB Viral Integration Site DataBase

VIS ID

TVIS10014751

Fusion event

HBV-DPP6 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

3084

Orient

+

Integrated sequence

GCCAGCAGCGCCTCCTCCTGCCTCTACCAATCGGCAGTCAGGAAGACAGCCTACTCCCATCTCTCCACCTCTAAGAGACAGTCATCCTCAGGCCATGCAG| |TGGAACTCCACAACATTCCACCAAGCTGTGCTAGATCCCAGAGTGAGGGGCCTATATCTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTGAACCCTGTTC

Chromosome

chr7

Cytoband

q36.2

Reference genome

Start

End

154265433/154568348 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-4668-5p ; hsa-mir-3153 ; hsa-mir-513b-3p ; hsa-mir-1276 ; hsa-mir-497-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-511-5p ; hsa-mir-6830-3p

Nearest miRNA

hsa-mir-10399/Upstream/3134709; hsa-mir-153-2/Downstream/3005988;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/263152, chr7-CpG: 22/Downstream/182001

Upstream sequence

TGTGTCATTGTTTTTATGAAAAAAGATTGCATTACAGACTCAGCAAAAAATTAACCATAGGAGAAAACTTATTGTAATTATTATTTTTGCTGACATTAAG

Downstream sequence

aaaagcctagaaagacaaattgatttcaggttatcctcctagagaatctttaatcatcggagcaccccgacagtgggatggaggtaatgagcattccgtt