Basic Information
VIS ID
TVIS10014754
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2009
Orient
+
Integrated sequence
GACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTC| |TGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCAC
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
57507944/56595385 (Hg38)
End
57507944/56595385 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-124-1/Upstream/13699110; hsa-mir-10400/Downstream/5119403;
Nearest TSS
ENST00000518652/Upstream/35562; ENST00000519314/Downstream/61080;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/147129, chr8-CpG: 77/Downstream/397756
Nearby gene
RPL37P6(-6604) ;
Upstream sequence
CAATGTCCACAGAAATAATTTCTGGTGTTCTTCATTCGATATCACGTCAAGGATAAGGATGAGCTAGTAAGCATTAAAACATATTTTCTTTTAAAGCAAT
Downstream sequence
TATAGTTATTGGTGAAATAAAAAAGGCAGCTTTGGGCACAGTAGCTAGAAGAACAAATATGTTTTCAGAGATTTTTGTAGTAATTAATTACTGGTGTTTT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate