Basic Information
VIS ID
TVIS10014758
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
649
Orient
-
Integrated sequence
TATGTTTCCCTCTTGTTGCTGTACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTCCTATGGGAGTGG| |GCCTCAGTCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGT
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
22353630/22342309 (Hg38)
End
22353630/22342309 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/836174; hsa-mir-11401/Downstream/1860807;
Nearest TSS
ENST00000527434/Upstream/10874; ENST00000566764/Downstream/7464;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/16054, chr16-CpG: 133/Downstream/31447
Nearby gene
POLR3E(-7206) ; CDR2(+3627) ;
Upstream sequence
ggcaatgatgttttgactgggacaccaaaagcacagacaaccaaagcaaaaacacaacaggactacctcaaacaaaagcttctgtacagcaaaggaaaca
Downstream sequence
acatgaaaaggcagcctacgcactgggagaaaatacttgcaaactatatatctaataaggggttactaaccaaaatatatagggaactcaatagcattca
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate